从事药理学研究四十余年的回顾

©1994-2009ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.:,,,?,,?,,,,,,,,,,,50,,,3912001323©1994-2009ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.!,20,,,,YMorris,,(LTP),,,,,1.:,,,,,,,,Rg1Rb1()LTP,,Rg1Rb110,,(iv)(ip)(),Rg1Rb1,,?5,Rg1Rb1M2,,,,M2,,,Rg1Rb1,M2,,Benishin,,HiroshiWata2nabe,Rg1Rb14,,Rg1Rb1CA3,Rg1,LTP,,45,,48(1993)(1998)SCI2.:(A),VitEVitC,4912001323©1994-2009ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.:BaxCCaspase,,,,,,,(redox),,,A?3.:,r,S2R2thalidomide(),,S2,,,,(523,6),,,,(-)(+)()50100mg/kg,(-)5mg/kg,(+),(-),,LTPBDNF,,(+),LD,,LTP10-8mol/LDL,,DL,L,,,,,,5912001323©1994-2009ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.:,,,,,,,,,,,,,,,,1998(IUPHAR)()15,,,,2006,,,,,ServierServier,8,1199732Servier,,,,,,,,,,,30,,,:,,,2545,,,,,,;,;,;,,,,,,,,,,,,,,,:,,,,,,,,,,,,6912001323